SUPARTZ^® Joint Fluid Therapy was the first hyaluronic acid commercially available for human use in treating osteoarthritis. More than 170 million SUPARTZ^® injections have been sold worldwide since its introduction in Japan in 1987. This wealth of clinical experience provides you and your patients with the confidence and reliability you get when you use the world’s most prescribed joint fluid therapy.

SUPARTZ^® is used for the treatment of pain in osteoarthritis of the knee in patients who have failed to get adequate relief from simple painkillers or from exercise and physical therapy.

SUPARTZ^® is a solution made of highly purified, sodium hyaluronate (hyaluronan). Hyaluronan is a natural chemical found in the body and is found in particularly high amounts in joint tissues and in the fluid (synovial fluid) that fills the joints. The body’s own hyaluronan acts like a lubricant and shock absorber in synovial fluid of a healthy joint. Osteoarthritis reduces your synovial fluid’s ability to protect and lubricate your joint. An injection of SUPARTZ^® is administered into your knee once a week for 3 to 5 weeks (for up to a total of 5 injections), as determined by your physician.*

SUPARTZ^® is a trademark of Seikagaku Corporation

*Some patients may experience benefit with 3 injections given at weekly intervals. This has been noted in a study in which patients treated with 3 injections were followed for 90 days.