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EXOGEN*

Bone Healing System

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EXOGEN Bone Healing System uses a mechanical force to stimulate mechanical receptors, producing a biological response

During the use of EXOGEN^◊ Bone Healing System, mechanical pressure waves transmit through skin and soft tissue. Cell receptors known as integrins are then activated, causing molecules to cluster. This clustering then starts an intra-cellular cascade during which molecules that regulate gene expression are stimulated and move into the nucleus to perform their function. This activity results in stimulated production of a range of genes and growth factors, which are critical to the bone healing process.

Mechanical pressure wave transmission
Mechanical pressure wave transmission

Integrin signal reception Integrin signal reception

Clustered integrins Clustered integrins

Molecules regulating gene expression are activated and migrate to the nucleus Molecules regulating gene expression are activated and migrate to the nucleus

Result: increased protein expression Result: increased protein expression