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Proven Performance | Simplicity | Versatility

What is CARGEL Bioscaffold?

CARGEL Bioscaffold is an easy, ready-to-use product applied during a single-step bone marrow stimulation procedure. It is easily prepared by mixing a buffer, a chitosan solution and the patient’s whole blood to create a liquid bioscaffold, resulting in superior cartilage repair.1,2

How does CARGEL Bioscaffold work?

  • Physically stabilizes a more voluminous blood clot
  • Provides structural framework for subsequent cellular ingrowth
  • Impedes blood clot retraction
  • Generates an adhesive bond between clot and surrounding cartilage

    Why choose CARGEL Bioscaffold?

    Proven Performance
    - Superiority to microfracture in lesion fill and quality of repair tissue at
      1 and 5 years1
    - Clinical improvement versus baseline1

    - Single-step system2
    - Liquid scaffold conforms to any lesion shape

    - Arthroscopic or mini-open
    - Suited for most cartilage lesions in the knee joint*

    *Please refer to the Instructions for Use (IFU) for a complete list of indications and contraindications.



    1. Shive, M., MD, et al. BST-CarGel Treatment Maintains Cartilage Repair Superiority over Microfracture at 5 Years in a Multicenter Randomized Controlled Trial. Cartilage 2015; Vol 6(2) 62-72

    2. M. Steinwachs, MD. Arthroscopic Treatment of Cartilage Lesions With Microfracture and BST-CarGel. Arthroscopy Techniques. 2014 Vol. 3(3): 399-402

    3. Stanish, W., MD, et. al. Novel Scaffold-Based BST-CarGel Treatment Results in Superior Cartilage Repair Compared with Microfracture in a Randomized Controlled Trial. JBJS, 2013;95:1640-50

    4. Animal studies have suggested early stage enhanced wound healing effects of BST-CarGel. Chevrier et al., Osteoarthritis Cartilage 2007

    Clinical Evidence

    CARGEL Bioscaffold Clinical Evidence

    CARGEL is an advanced bioscaffold technology for enhancing cartilage regeneration and is supported by Level 1 clinical evidence demonstrating improved quantity and quality of tissue repair over microfracture alone at 5 years post-op1.


    CARGEL Videos

    CARGEL Bioscaffold Educational Videos and Testimonial

    CARGEL is an easy to use, off the shelf product indicated for use in cartilage repair procedures. It is designed to be applied through a minimally invasive, one-step cartilage repair procedure.


    CARGEL Bioscaffold Surgical Technique

    CARGEL Bioscaffold Steinwachs Arthroscopy

    CARGEL Bioscaffold MOA Animation

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    CARGEL Bioscaffold is not available in the United States

    For product availability, please select your country from the list here